Overview

An introduction of NExtSEEK and overview of our ongoing data management efforts

NExtSEEK is an active data management platform based out of the MIT BioMicro Center: the Integrated Genomics/Bioinformatics Core Facility of the Koch Institute for Integrative Cancer Research.

NExtSEEK is a modified wrapper, built on the SEEK Infrastructure, to allow for active data management of ongoing research projects. Our focus is to ensure that the data associated with these research projects is FAIR: Findable, Accessible, Interopable, and Reusable. This is achieved by structuring metadata in a relational model, allowing for the creation and maintenance of a rich provenance for data files.

Currently, we support data management for 5 projects:

• HI-IMPAcTB

• The MIT SuperFunder Research Program (SRP)

• Metastasis Network of Cancer (MetNet)

• Cancer System Biology Consortium (CSBC)

• Break Through Cancer (BTC)

NExtSEEK is maintained as a private instance that hosts pre-publication research data and is only accessible to those who have federated access. Users from one project cannot see or access data files / metadata of other projects. If you are a member of one the projects above and would like to register for a NExtSEEK account, head to Account Registration / Project Association:

If you are looking to set up your own NExtSEEK instance, head to the installation page.

Published data of these projects exist in FAIRDOMHub - a metadata repository maintained by the SEEK team. Links to the public data are below:

• IMPAcTB

• SRP

• MetNet

Summary Statistics as of August 2024:

Project	Sample Count
IMPAcTB	58711
SRP	32294
MetNet	4885
CSBC	302
BTC	892

Statistic	Sample Count
Samples	100843
Raw Data File Samples	23993
Analyzed Data File Samples	1141
FAIRDOMHub Studies	30
Public FAIRDOMHub Studies	19

Sample Type Counts - by Clade (across all projects)